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AKA-12
Osimertinib Mesylate
Cat. No.
AKA-12
CAS No.
1421373-66-1
MF
C29H37N7O5S
MW
595.719
Osimertinib mesylate is a third‑generation EGFR inhibitor that suppresses the T790M resistance mutation generated by second‑generation EGFR inhibitors.
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Technical Data
Description
Storage and Shipping
References
Product Name
Osimertinib Mesylate
CAS No.
1421373-66-1
MF
C29H37N7O5S
MW
595.719
Specification
99%
Research Area
Oncology
Description
Osimertinib mesylate is a third‑generation EGFR inhibitor that suppresses the T790M resistance mutation generated by second‑generation EGFR inhibitors. Packing: 1kg/bag; 25kg/drum or as request Availability: In stock
Documents
Certificate of Analysis (COA), API specification, Safety Data Sheet (SDS/MSDS), evidence of GMP compliance, Stability data / Stability summary, etc.
Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Cross DA, et al. AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cancer Discovery. 2014 Sep;4(9):1046-61.
[2]. [2]Hirano T, et al. Pharmacological and Structural Characterizations of Naquotinib, a Novel Third-Generation EGFR Tyrosine Kinase Inhibitor, in EGFR-Mutated Non-Small Cell Lung Cancer. Molecular Cancer Therapeutics. 2018 Apr;17(4):740-750.
[2]. [2]Hirano T, et al. Pharmacological and Structural Characterizations of Naquotinib, a Novel Third-Generation EGFR Tyrosine Kinase Inhibitor, in EGFR-Mutated Non-Small Cell Lung Cancer. Molecular Cancer Therapeutics. 2018 Apr;17(4):740-750.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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